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George de Hevesy used isotopes to study cancer

After fleeing to Sweden in 1943, George de Hevesy used labelled atoms to study how X-rays affect nucleic acids in tumours and how iron moves in healthy and cancerous tissue.

George de Hevesy
George de Hevesy · 1885–1966
Person
George de Hevesy
Lived
1885–1966
Field
Radiochemistry
From
Hungarian

The story

George de Hevesy, born in Budapest in 1885 into a family of Hungarian-Jewish descent, had spent three decades developing the radioactive tracer: a small amount of a radioactive isotope mixed with an ordinary element so that its path through a chemical reaction, a plant or an animal could be followed. From 1934, at Niels Bohr's institute in Copenhagen, he used labelled atoms in numerous studies of plant and animal physiology.

By 1943, with Denmark under German occupation, Copenhagen was no longer safe for a scientist of Jewish descent, and de Hevesy fled to neutral Sweden. He settled in Stockholm as an associate of the Institute of Research in Organic Chemistry and worked at Stockholm University until 1961. He was received there by the chemist Hans von Euler-Chelpin, a Nobel laureate himself, and the two wrote many papers together during and after the war. That same year, 1943, de Hevesy was awarded the Nobel Prize in Chemistry for his work on isotopes as tracers.

In Sweden he continued his labelled-atom research with support from the Swedish State Research Council and the Wallenberg Foundation. Among other things he studied the effect of X-rays on the formation of nucleic acid in tumours and in normal organs, and the transport of iron in healthy and cancerous organisms.

This research used his tracer method to ask practical questions about cancer and radiation, the kind of questions that underlie modern radiotherapy and nuclear medicine. He also wrote several important books on radiochemistry and published some 397 scientific works over his career.

De Hevesy continued as an active scientific associate of Stockholm University into his retirement. He became an honorary fellow of the British Institute of Radiology and of the American Society of Nuclear Medicine, and in 1958 received the Atoms for Peace Award. Medical scientists later called him the father of nuclear medicine.

Why it matters

De Hevesy's tracer studies of tumours helped open the way for the use of isotopes in understanding and treating cancer.

About George de Hevesy

Hungarian chemist of Jewish origin who invented radioactive tracers, co-discovered hafnium, hid two Nobel medals from the Nazis in acid, and won the 1943 Nobel Prize in Chemistry.

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George de Hevesy
1885–1966 · Radiochemistry
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Another act of tikkun olam. This is part of tikkun olam, the Jewish idea of repairing the world, and every one of us can add to it.

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