Did you know? · Science & Medicine

George de Hevesy ran the first radioactive tracer experiment

In early 1913, with Friedrich Paneth at the Vienna Institute for Radium Research, George de Hevesy carried out the first radioactive-tracer experiment.

George de Hevesy
George de Hevesy · 1885–1966
Person
George de Hevesy
Lived
1885–1966
Field
Radiochemistry
From
Hungarian

The story

George de Hevesy was born in Budapest in 1885 into a wealthy family of Hungarian-Jewish descent; his grandparents on both sides had led the Jewish community of Pest. He studied in Budapest, Berlin and Freiburg, where he earned his doctorate in 1908, and spent time in Fritz Haber's laboratory in Karlsruhe. In 1910 he went to study radioactivity under Ernest Rutherford in Manchester, where he also met Niels Bohr and where his work concerned radium and lead isotopes.

Work with radioactive substances taught him that a radioactive isotope of an element behaves chemically exactly like the ordinary, stable element. That suggested an idea. If a tiny amount of the radioactive form is mixed in, it can be followed by its radiation, revealing where the element goes and how it reacts. Because radioactive decay releases far more energy than any chemical reaction, even a very low concentration of the labelled atoms can be picked up by sensitive radiation detectors.

Early in 1913 he interrupted his studies in Manchester to work with Friedrich Paneth at the Vienna Institute for Radium Research. Together they carried out the first radioactive-tracer experiment. During his stay in Vienna he also qualified to lecture at the University of Budapest, and in 1915 he was drafted into the Austro-Hungarian army.

The method allowed scientists to watch particular kinds of atoms at work without disturbing the processes they were studying. De Hevesy spent much of the rest of his career extending it. In 1923 he used radioactive lead to trace how broad bean plants take up lead, the first use of a tracer in biology. Later he helped bring isotopes into clinical medicine, and once artificial radioisotopes became available in the 1930s he applied them to plant and animal physiology.

In 1943 he was awarded the Nobel Prize in Chemistry for his work on the use of isotopes as tracers in the study of chemical processes. Medical scientists have called him the father of nuclear medicine, and in 2005 a Danish isotope laboratory was named after him as the father of the tracer principle.

Why it matters

The radioactive tracer became one of the most widely used methods in chemistry, biology and medicine, and a cornerstone of nuclear medicine.

About George de Hevesy

Hungarian chemist of Jewish origin who invented radioactive tracers, co-discovered hafnium, hid two Nobel medals from the Nazis in acid, and won the 1943 Nobel Prize in Chemistry.

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George de Hevesy
1885–1966 · Radiochemistry
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Another act of tikkun olam. This is part of tikkun olam, the Jewish idea of repairing the world, and every one of us can add to it.

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