Did you know? · Science & Medicine

Otto Stern's lab trained Rabi, opening a path to MRI

Isidor Rabi learned the molecular-beam technique in Otto Stern's Hamburg lab, and built on it the magnetic resonance method behind NMR, MRI and atomic clocks.

Otto Stern
Otto Stern · 1888–1969
Person
Otto Stern
Lived
1888–1969
Field
Experimental physics
From
German-American

The story

Isidor Isaac Rabi was born in 1898 in Rymanów, in what was then Austria-Hungary, and grew up on New York's Lower East Side. After a doctorate at Columbia University he went to Europe in 1927 to learn the new quantum physics. In Copenhagen, Niels Bohr arranged for him and Yoshio Nishina to work with the theorist Wolfgang Pauli at the University of Hamburg.

There Rabi found Otto Stern's molecular-beam laboratory, then one of the leading centres of physics in the world, and was drawn into its experiments through Stern's two English-speaking fellows, Ronald Fraser and John Bradshaw Taylor. Stern's group used uneven magnetic fields that were hard to control and measure. Rabi came up with a cleverer arrangement, using a uniform field with the beam entering at a glancing angle, so that atoms would be deflected like light through a prism. He explained the idea to Stern, who invited him to do the experiment, and with Taylor's help it worked. Stern insisted that Rabi publish first in Nature under his own name, so that no one would think it was Stern's work. The letter appeared in February 1929. Rabi later said that from Stern and Pauli he learned what physics should be.

Back at Columbia, Rabi built on Stern's methods. In 1937 he and his students devised the molecular-beam magnetic resonance method, using a radio-frequency field to flip the orientation of atomic nuclei between two magnets. It measured nuclear magnetic properties with great precision and won him the 1944 Nobel Prize in Physics. In 1945 he proposed using atomic resonance to build clocks, and such atomic clocks were soon made. Several of his students and colleagues, including Polykarp Kusch, Norman Ramsey and Charles Townes, went on to win Nobel Prizes of their own.

Rabi's method led to nuclear magnetic resonance spectroscopy and to magnetic resonance imaging. Near the end of his life, Rabi himself was examined in an MRI scanner and remarked that he had never thought his work would come to this.

Its roots run back to Stern's Hamburg laboratory, where a visiting American learned to work with beams of atoms and was encouraged to try his own ideas. The 2011 history of Stern's career notes that about 20 Nobel Prizes were eventually awarded for work based on the molecular-beam method.

Why it matters

Through Rabi, Stern's methods led to MRI scanners that help diagnose illness without radiation, and to atomic clocks that keep GPS and global communications in time.

About Otto Stern

Physicist whose molecular-beam method proved space quantisation in the Stern–Gerlach experiment and measured the proton’s magnetic moment; Nobel Prize in Physics 1943.

Read the full profile
Otto Stern
1888–1969 · Experimental physics
View profile →

More about Otto Stern

Sources

Another act of tikkun olam. This is part of tikkun olam, the Jewish idea of repairing the world, and every one of us can add to it.

More in Science & Medicine

On kindness & the treatment of others
“A friend is devoted at all times; a brother is born to share adversity.”
Proverbs 17:17