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Casimir Funk warned of hidden vitamin shortages

In his 1936 book Vitamin and Mineral Therapy, Casimir Funk warned that mild vitamin shortages could weaken the body's resistance to infection long before obvious disease appeared.

Casimir Funk
Casimir Funk · 1884–1967
Person
Casimir Funk
Lived
1884–1967
Field
Biochemistry
From
Polish-American

The story

By the 1930s scientists understood that a severe lack of a vitamin could cause scurvy, rickets, beriberi or pellagra. Casimir Funk, the Warsaw-born Jewish biochemist who had coined the word “vitamine” in 1912, had helped establish that idea. By the mid-1930s he was working in Paris, where he had founded a private laboratory, Casa Biochemica, and served as a biochemist for the Roussel company.

In 1936 he published Vitamin and Mineral Therapy, translated into English by his longtime collaborator H. E. Dubin. In it he described vitamin deficiencies as insidious, because they can develop without warning and cause lasting damage. He agreed that the lack of a particular vitamin eventually leads to a particular nutritional disease. But he argued that long before such a disease becomes apparent, a shortage of one or more vitamins usually causes tissue changes that lower the general resistance of the body and make it more susceptible to certain infections.

It was a forward-looking view of nutrition. Funk was arguing that adequate vitamins matter for everyone's everyday health and resistance to illness, not only for people already suffering from a named deficiency disease. The same year he determined the molecular structure of thiamine, vitamin B1, the substance whose absence causes beriberi.

Funk was also careful not to overstate the case. He stressed that only small amounts of vitamins are needed to maintain health, a point many people ignored during the vitamin craze that followed, when manufacturers promoted large doses even though too much of some vitamins, such as A and D, can be harmful.

After Germany invaded Poland in 1939 he returned to New York and resumed work with the U.S. Vitamin Corporation, which owned the copyright to Vitamin and Mineral Therapy. He went on to head the Funk Foundation for Medical Research, supported by the company, and retired from active research in 1963. His contributions helped improve child and adult nutrition and encouraged the addition of proper nutrients to manufactured foods.

Why it matters

Funk's warning helped shift nutrition toward prevention, encouraging attention to adequate vitamins for everyone rather than only treating severe disease.

About Casimir Funk

Warsaw-born biochemist of Jewish descent who coined the word ‘vitamine’ in 1912 and argued that beriberi, scurvy, pellagra and rickets were deficiency diseases.

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Casimir Funk
1884–1967 · Biochemistry
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Sources

Another act of tikkun olam. This is part of tikkun olam, the Jewish idea of repairing the world, and every one of us can add to it.

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